William Harrison Nebergall (21 December 1914 – 2 September 1978) was an inorganic chemist who synthesized the fluoride compatible polishing agent calcium pyrophosphate. This discovery combined with stannous fluoride led to the development and release of the first fluoride containing toothpaste, Crest, in 1955. In 1960 Crest became the first toothpaste to be endorsed by the American Dental Association as an effective decay-preventing agent. In 1959 he cowrote one of the first widely used textbooks of college chemistry titled ''General Chemistry'', which was published in six editions.
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William Harrison Nebergall (21 December 1914 – 2 September 1978) was an inorganic chemist who synthesized the fluoride compatible polishing agent calcium pyrophosphate. This discovery combined with stannous fluoride led to the development and release of the first fluoride containing toothpaste, Crest, in 1955. In 1960 Crest became the first toothpaste to be endorsed by the American Dental Association as an effective decay-preventing agent. In 1959 he cowrote one of the first widely used textbooks of college chemistry titled ''General Chemistry'', which was published in six editions.
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