Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization /

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasin...

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Bibliographic Details

Main Author:	Kerns, Edward Harvel
Corporate Author:	ScienceDirect (Online service)
Other Authors:	Di, Li
Format:	eBook
Language:	English
Published:	Amsterdam ; Boston : Academic Press, [2008]
Subjects:	Pharmaceutical chemistry. Drugs > Structure-activity relationships. Drug development. Drugs > Design. Drug Design. Drug Evaluation, Preclinical. Drug-Related Side Effects and Adverse Reactions. Pharmaceutical Preparations > metabolism. Pharmacokinetics. Structure-Activity Relationship. Electronic books.
Online Access:	Connect to the full text of this electronic book Publisher description