Drug-like properties : concepts, structure design and methods : from ADME to toxicity optimization /

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasin...

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Bibliographic Details
Main Author: Kerns, Edward Harvel
Corporate Author: ScienceDirect (Online service)
Other Authors: Di, Li
Format: eBook
Published: Amsterdam ; Boston : Academic Press, [2008]
Online Access:Connect to the full text of this electronic book
Publisher description
Table of Contents:
  • Preface; Introductory Concepts; Physicochemical Properties; Disposition, Metabolism and Safety; Methods; Specific Topics; Answers to Problems; Appendix I: General References; Appendix II: Glossary.