Pharmaceutical toxicology in practice : a guide for non-clinical development /

This book describes, with references to key source materials, €the background to, and conduct of, the principal nonclinical studies€that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on descripti...

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Bibliographic Details
Other Authors: Lodola, Alberto, Stadler, Jeanne
Format: eBook
Language:English
Published: Hoboken, N.J. : Wiley, [2011]
Series:Wiley online library.
Subjects:
Online Access:Connect to the full text of this electronic book

MARC

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245 0 0 |a Pharmaceutical toxicology in practice :  |b a guide for non-clinical development /  |c edited by Alberto Lodola, Jeanne Stadler. 
264 1 |a Hoboken, N.J. :  |b Wiley,  |c [2011] 
264 4 |c ©2011 
300 |a 1 online resource (vi, 258 pages) :  |b illustrations 
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504 |a Includes bibliographical references and index. 
505 0 |a Frontmatter -- Introduction / Alberto Lodola, Jeanne Stadler -- The Regulatory Environment / Claudio Bernardi, Marco Brughera -- Toxicological Development: Roles and Responsibilities / Franck Chuzel, Bernard Ruty -- Contract Research Organizations / Maurice Cary -- Safety Pharmacology / Claudio Arrigoni, Valeria Perego -- Formulations, Impurities, and Toxicokinetics / Claude Charuel -- General Toxicology / Alberto Lodola -- Genetic Toxicology / Peggy Guzzie-Peck, Jennifer C Sasaki, Sandy K Weiner -- Developmental and Reproductive Toxicology / Jeanne Stadler -- Data Analysis, Report Writing, and Regulatory Documentation / Monique Y Wells -- Risk Management / Alberto Lodola -- Index. 
520 |a This book describes, with references to key source materials, €the background to, and conduct of, the principal nonclinical studies€that are central to drug development. The chapters provide an understanding of the key components of the preclinical phase of drug development with a hands-on description, with core chapters addressing study conduct, types, and reporting. As such, it is a practical guide through toxicology testing and an up-to-date reference on current issues, new developments, and future directions in toxicology. Opening with a practical description of toxicology and its. 
588 |a Description based on print version record. 
650 1 2 |a Drug Evaluation, Preclinical  |x standards.  |0 https://id.nlm.nih.gov/mesh/D004353Q000592 
650 1 2 |a Drug-Related Side Effects and Adverse Reactions.  |0 https://id.nlm.nih.gov/mesh/D064420 
650 2 2 |a Toxicity Tests  |x standards.  |0 https://id.nlm.nih.gov/mesh/D018675Q000592 
650 0 |a Drugs  |x Toxicity testing. 
650 4 |a Drug Evaluation, Preclinical  |x standards. 
650 4 |a Drug Toxicity. 
650 4 |a Drugs  |x Toxicity testing. 
650 4 |a Health. 
650 4 |a Medicine. 
650 4 |a Pharmacy. 
650 4 |a Social Science. 
650 4 |a Toxicity Tests  |x standards. 
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700 1 |a Stadler, Jeanne.  |0 http://id.loc.gov/authorities/names/n2010181983 
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