In Vivo Inhalation Toxicity Screening Methods for Manufactured Nanomaterials /

This edited volume discusses the short-term inhalation study (STIS) and intratracheal administration, the two major in vivo inhalation-toxicity screening methods, which play an important role in efficient hazard evaluation. It also provides a general overview of the inhalation toxicity of nanomateri...

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Bibliographic Details
Corporate Author: SpringerLink (Online service)
Other Authors: Takebayashi, Toru (Editor), Landsiedel, Robert (Editor), Gamo, Masashi (Editor)
Format: eBook
Language:English
Published: Singapore : Springer Singapore : Imprint: Springer, 2019.
Edition:1st ed. 2019.
Series:Current Topics in Environmental Health and Preventive Medicine,
Subjects:
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • 1 The role of in vivo screening studies in assessing manufactured nanomaterials
  • Part 1 Short Term Inhalation Study
  • 2. The short-term inhalation study (STIS) as a range finder and screening tool in a tiered grouping strategy
  • 3. Use of short-term inhalation study to obtain initial hazard data and prepare for subacute and subchronic inhalation studies, and toxicokinetic studies
  • 4. Subchronic inhalation Toxicity Study with a Vapor Grown Carbon Nanofiber in Male and Female Rats (OECD 413) - Does nanofiber exposure have adverse impacts on the cardiovascular system?
  • Part 2 Intratracheal Administration Study
  • 5. Comparison of responses in rat lung following inhalation and intratracheal administration of nanoparticles
  • 6. Standardization of intratracheal instillation study of manufactured nanomaterials
  • 7. Sample preparation and the chracterization for Intratracheal Administration
  • 8. Development of intra-tracheal intra-pulmonary spraying (TIPS) as an alternative assay method for testing chronic toxicity and carcinogenic potential of multiwall carbon nanotubes
  • 9. Equivalence Criteria for Nanomaterials Developed from Results of a Comparative Study using Intratracheal Administration
  • 10. Toxicokinetics of nano materials after the intratracheal administration
  • 11. In Vitro Alveolar Epithelial Models toward the Prediction of Cytotoxicity Tests and Translocation Studies of Nanoparticles. .