Molecular neuropharmacology : strategies and methods /

Bibliographic Details
Other Authors: Schousboe, Arne, Bräuner-Osborne, Hans
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2004]
Subjects:

MARC

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245 0 0 |a Molecular neuropharmacology :  |b strategies and methods /  |c edited by Arne Schousboe and Hans Bräuner-Osborne. 
264 1 |a Totowa, N.J. :  |b Humana Press,  |c [2004] 
264 4 |c ©2004 
300 |a xi, 271 pages :  |b illustrations ;  |c 27 cm. 
336 |a text  |2 rdacontent  |b txt 
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504 |a Includes bibliographical references and index. 
505 0 |a Computational studies of ligand-receptor interactions in ionotropic glutamate receptors -- Delineation of the physiological role of kainate receptors by use of subtype selective ligands -- Molecular pharmacology of the metabotropic glutamate receptors -- Functional characterization of GABA receptor ligands in vitro : correlation with in vivo activity -- In vivo function of GABA receptor subtypes unraveled with mutant mice -- Characterization of the GABA receptor recognition site through ligand design and pharmacophore modeling -- The GABA receptor : from cloning to knockout mice -- Structure and molecular characterization of the substrate-binding sites of the dual-function glutamate transporters -- Allosteric modulation of glutamate transporters -- Characterization of the substrate-binding site in GABA transporters -- Insights from endogenous and engineered Zn²⁺ binding sites in monoamine transporters -- A structural context for studying neurotransmitter transporter function -- Functional mechanisms of G protein-coupled receptors in a structural context 
650 2 |a Neuropharmacology  |x methods. 
650 2 |a Receptors, Neurotransmitter. 
650 2 |a Neurotransmitter Agents. 
650 2 |a Receptors, GABA. 
650 2 |a Receptors, Glutamate. 
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700 1 |a Bräuner-Osborne, Hans. 
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