Molecular neuropharmacology : strategies and methods /

Bibliographic Details
Other Authors: Schousboe, Arne, Bräuner-Osborne, Hans
Format: Book
Language:English
Published: Totowa, N.J. : Humana Press, [2004]
Subjects:
Table of Contents:
  • Computational studies of ligand-receptor interactions in ionotropic glutamate receptors
  • Delineation of the physiological role of kainate receptors by use of subtype selective ligands
  • Molecular pharmacology of the metabotropic glutamate receptors
  • Functional characterization of GABA receptor ligands in vitro : correlation with in vivo activity
  • In vivo function of GABA receptor subtypes unraveled with mutant mice
  • Characterization of the GABA receptor recognition site through ligand design and pharmacophore modeling
  • The GABA receptor : from cloning to knockout mice
  • Structure and molecular characterization of the substrate-binding sites of the dual-function glutamate transporters
  • Allosteric modulation of glutamate transporters
  • Characterization of the substrate-binding site in GABA transporters
  • Insights from endogenous and engineered Zn²⁺ binding sites in monoamine transporters
  • A structural context for studying neurotransmitter transporter function
  • Functional mechanisms of G protein-coupled receptors in a structural context