Chirality in drug research /

Bibliographic Details
Other Authors: Francotte, Eric, Lindner, W. (Wolfgang)
Format: Book
Language:English
Published: Weinheim : Wiley-VCH, [2006]
Series:Methods and principles in medicinal chemistry ; 33.
Subjects:

MARC

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245 0 0 |a Chirality in drug research /  |c edited by Eric Francotte and Wolfgang Lindner. 
264 1 |a Weinheim :  |b Wiley-VCH,  |c [2006] 
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300 |a xix, 351 pages :  |b illustrations, portrait ;  |c 25 cm. 
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490 1 |a Methods and principles in medicinal chemistry ;  |v 33 
504 |a Includes bibliographical references and index. 
505 0 |a Chiral drugs from a historical point of view -- Stereoselective synthesis of drugs - an industrial perspective -- Aspects of chirality in natural products drug discovery -- Biotransformation methods for preparing chiral drugs and drug intermediates -- Resolution of chiral drugs and drug intermediates by crystallisation -- Isolation and production of optically pure drugs by enantioselective chromatography -- Stereoselective chromatographic methods for drug analysis -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or ¹H NMR anisotropy methods -- Keywords in chirality modeling molecular modeling of chirality - software and literature research on chirality in modeling, chirality in docking, chiral ligand - receptor interaction and symmetry 
650 0 |a Drugs  |x Research. 
650 0 |a Drug development. 
650 0 |a Chirality. 
650 2 |a Drug Design. 
650 2 |a Molecular Conformation. 
650 2 |a Stereoisomerism. 
700 1 |a Francotte, Eric. 
700 1 |a Lindner, W.  |q (Wolfgang) 
830 0 |a Methods and principles in medicinal chemistry ;  |v 33. 
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