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|a 3527310762
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|a 9783527310760
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|a QV 744
|b C541 2006
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|a 615.19
|2 22
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|a Chirality in drug research /
|c edited by Eric Francotte and Wolfgang Lindner.
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264 |
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1 |
|a Weinheim :
|b Wiley-VCH,
|c [2006]
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264 |
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4 |
|c ©2006
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300 |
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|a xix, 351 pages :
|b illustrations, portrait ;
|c 25 cm.
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336 |
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|a text
|2 rdacontent
|b txt
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337 |
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|a unmediated
|2 rdamedia
|
338 |
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|a volume
|2 rdacarrier
|b nc
|
490 |
1 |
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|a Methods and principles in medicinal chemistry ;
|v 33
|
504 |
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|a Includes bibliographical references and index.
|
505 |
0 |
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|a Chiral drugs from a historical point of view -- Stereoselective synthesis of drugs - an industrial perspective -- Aspects of chirality in natural products drug discovery -- Biotransformation methods for preparing chiral drugs and drug intermediates -- Resolution of chiral drugs and drug intermediates by crystallisation -- Isolation and production of optically pure drugs by enantioselective chromatography -- Stereoselective chromatographic methods for drug analysis -- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis -- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or ¹H NMR anisotropy methods -- Keywords in chirality modeling molecular modeling of chirality - software and literature research on chirality in modeling, chirality in docking, chiral ligand - receptor interaction and symmetry
|
650 |
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|a Drugs
|x Research.
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650 |
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0 |
|a Drug development.
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650 |
|
0 |
|a Chirality.
|
650 |
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2 |
|a Drug Design.
|
650 |
|
2 |
|a Molecular Conformation.
|
650 |
|
2 |
|a Stereoisomerism.
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700 |
1 |
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|a Francotte, Eric.
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700 |
1 |
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|a Lindner, W.
|q (Wolfgang)
|
830 |
|
0 |
|a Methods and principles in medicinal chemistry ;
|v 33.
|
999 |
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|a MARS
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999 |
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|a Texas A&M University
|b Rellis Campus
|c Joint Library Facility
|d Remote Storage
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|e QV 744 C541 2006
|h National Library of Medicine classification
|i unmediated -- volume
|m 323890192935B
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