Chirality in drug research /
| Other Authors: | , |
|---|---|
| Format: | Book |
| Language: | English |
| Published: |
Weinheim :
Wiley-VCH,
[2006]
|
| Series: | Methods and principles in medicinal chemistry ;
33. |
| Subjects: |
Table of Contents:
- Chiral drugs from a historical point of view
- Stereoselective synthesis of drugs - an industrial perspective
- Aspects of chirality in natural products drug discovery
- Biotransformation methods for preparing chiral drugs and drug intermediates
- Resolution of chiral drugs and drug intermediates by crystallisation
- Isolation and production of optically pure drugs by enantioselective chromatography
- Stereoselective chromatographic methods for drug analysis
- Capillary electrophoresis coupled to mass spectrometry for chiral drugs analysis
- Powerful chiral molecular tools for preparation of enantiopure alcohols and simultaneous determination of their absolute configurations by X-ray crystallography and/or ¹H NMR anisotropy methods
- Keywords in chirality modeling molecular modeling of chirality - software and literature research on chirality in modeling, chirality in docking, chiral ligand - receptor interaction and symmetry