|
|
|
|
| LEADER |
00000nam a2200000 a 4500 |
| 001 |
in00004680260 |
| 006 |
m o d |
| 007 |
cr |n||||||||| |
| 008 |
121227s2013 njuaf ob 001 0 eng d |
| 005 |
20230506170331.6 |
| 035 |
|
|
|a wil6007436
|
| 035 |
|
|
|a (NhCcYBP)wil6007436
|
| 040 |
|
|
|a NhCcYBP
|b eng
|c NhCcYBP
|
| 020 |
|
|
|a 9781118516157
|
| 020 |
|
|
|a 111851615X
|
| 020 |
|
|
|a 9781118516126
|
| 020 |
|
|
|a 1118516125
|
| 020 |
|
|
|a 9781283917520
|
| 020 |
|
|
|a 1283917521
|
| 020 |
|
|
|z 9780470942383
|
| 020 |
|
|
|z 047094238X
|
| 037 |
|
|
|a 10.1002/9781118516157
|b Wiley InterScience
|n http://www3.interscience.wiley.com
|
| 050 |
|
4 |
|a RS189.5.S65
|b M37 2013eb
|
| 060 |
1 |
0 |
|a QV 745
|
| 072 |
|
7 |
|a MED
|x 023000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 058170
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 071000
|2 bisacsh
|
| 072 |
|
7 |
|a MED
|x 072000
|2 bisacsh
|
| 082 |
0 |
4 |
|a 615.1
|a 615.19
|
| 245 |
0 |
0 |
|a Mass spectrometry for drug discovery and drug development /
|c edited by Walter A. Korfmacher.
|
| 260 |
|
|
|a Hoboken, N.J. :
|b Wiley,
|c 2013.
|
| 300 |
|
|
|a 1 online resource (xii, 461 pages, [16] pages of plates)) :
|b illustrations (some color).
|
| 336 |
|
|
|a text
|b txt
|2 rdacontent
|
| 337 |
|
|
|a computer
|b c
|2 rdamedia
|
| 338 |
|
|
|a online resource
|b cr
|2 rdacarrier
|
| 490 |
1 |
|
|a Wiley series on mass spectrometry
|
| 588 |
0 |
|
|a Print version record.
|
| 520 |
|
|
|a This book presents a summary of the ways mass spectrometry is used in various stages of drug discovery and development including early support of medicinal chemistry, drug metabolism studies, distribution, degradation, and various development assays. The book includes a balance of basic and advanced information. Specific chapters relate to various stages in the process (e.g., discovery) as well as chapters on topics of current interest (lipidomics and SiRNA) are covered.
|
| 504 |
|
|
|a Includes bibliographical references and index.
|
| 505 |
0 |
|
|a 1. Overview of the various types of mass spectrometers that are used in drug discovery and drug development / Gerard Hopfgartner -- 2. Utility of high resolution mass spectrometry for new drug discovery applications / William Bart Emary and Nanyan Rena Zhang -- 3. Quantitative mass spectrometry considerations in a regulated environment / Mohammed Jemal and Yuan-Qing Xia -- 4. Mass spectrometry for quantitative in vitro ADME assays / Jun Zhang and Wilson Z. Shou -- 5. Metabolite identification using mass spectrometry in drug development / Natalia Penner, Joanna Zgoda-Pols, and Chandra Prakash -- 6. MS analysis of biological drugs, proteins, and peptides / Yi Du, John Mehl, and Pavlo Pristatsky -- 7. Characterization of impurities and degradation products in small molecule pharmaceuticals and biologics / Hui Wei, Guodong Chen and Adrienne A. Tymiak -- 8. Liquid extraction surface analysis (LESA) : a new mass spectrometry-based technique for ambient surface profiling / Dan Eikel and Jack Henion -- 9. MS applications in support of medicinal chemistry sciences / Maarten Honing, Benno Ingelse, and Birendraÿ N. Pramanik -- 10. Imaging mass spectrometry of proteins and peptides / Michelle L. Reyzer and Richard M. Caprioli -- 11. Imaging mass spectrometry for drugs and metabolites / Stacey R. Oppenheimer -- 12. Screening reactive metabolites : role of liquid chromatography-high resolution mass spectrometry in combination with 'intelligent' data mining tools / Shuguang Ma and Swapan K. Chowdhury -- 13. Mass spectrometry of siRNA / Mark Cancilla and Mike Flanagan -- 14. Mass spectrometry for metabolomics / Petia Shipkova and Michael D. Reily -- 15. Quantitative analysis of peptides with mass spectrometry : selected reaction monitoring or high resolution full scan? / Lieve Dillen and Filip Cuyckens.
|
| 650 |
|
0 |
|a Drugs
|x Analysis.
|
| 650 |
|
0 |
|a Drug development.
|
| 650 |
|
0 |
|a Mass spectrometry.
|
| 650 |
1 |
2 |
|a Drug Discovery.
|
| 650 |
1 |
2 |
|a Mass Spectrometry
|x methods.
|
| 650 |
2 |
2 |
|a Peptides
|x analysis.
|
| 650 |
2 |
2 |
|a Pharmaceutical Preparations
|x analysis.
|
| 650 |
2 |
2 |
|a Proteins
|x analysis.
|
| 655 |
|
4 |
|a Electronic books.
|
| 700 |
1 |
|
|a Korfmacher, Walter A.
|
| 776 |
0 |
8 |
|i Print version:
|t Mass spectrometry for drug discovery and drug development.
|d Hoboken, N.J. : John Wiley & Sons, ©2013
|z 9780470942383
|w (DLC) 2012031775
|
| 830 |
|
0 |
|a Wiley-Interscience series on mass spectrometry.
|
| 856 |
4 |
0 |
|u http://proxy.library.tamu.edu/login?url=https://onlinelibrary.wiley.com/book/10.1002/9781118516157
|z Connect to the full text of this electronic book
|t 0
|
| 955 |
|
|
|a Wiley EBA record
|
| 975 |
|
|
|p Wiley UBCM Full Collection 2023
|
| 976 |
|
|
|a 6007436
|
| 999 |
f |
f |
|s ee9880d7-95d0-45ee-9ac1-f4dc98d93f1c
|i cab8dcac-ba37-4e3f-9f1e-d107057d688a
|t 0
|
| 952 |
f |
f |
|a Texas A&M University
|b College Station
|c Electronic Resources
|d Available Online
|t 0
|e RS189.5.S65 M37 2013eb
|h Library of Congress classification
|
| 998 |
f |
f |
|a RS189.5.S65 M37 2013eb
|t 0
|l Available Online
|