Remodelling the cavity of a transmembrane pore by genetic engineering /

The cavity within the transmembrane staphylococcal a-hemolysin (aHL) pore is roughly a sphere of diameter ~45 Š(volume ~32,600 ų). The alpha-hemolysin gene was modified to introduce exogenous polypeptide sequences between positions 105 and 106 of aHL. These modified aHLs were assembled either by t...

Full description

Bibliographic Details

Main Author:	Jung, Yunhee, 1968-
Other Authors:	Bayley, Hagan (Thesis advisor), Pace, C. Nick (Thesis advisor)
Format:	Thesis eBook
Language:	English
Published:	[College Station, Tex.] : [Texas A&M University], [2006]
Subjects:	Major medical sciences. re-design alpha-hemolysin
Online Access:	Link to OAK Trust copy