Design and analysis of vaccine studies /

Design and analysis of vaccine studies /

Bibliographic Details
Main Author: Halloran, M. Elizabeth
Corporate Author: SpringerLink (Online service)
Other Authors: Longini, Ira M., Struchiner, Claudio J.
Format: eBook
Language:English
Published: New York : Springer, 2009.
Series:Statistics for biology and health.
Subjects:
Research Design.
Vaccines.
Clinical Trials as Topic.
Drug Evaluation > methods.
Statistics as Topic.
Case-control method.
Epidemiology > Research.
Vaccines > Research.
Vaccines > Statistical methods.
Electronic books.
Online Access:Connect to the full text of this electronic book
Table of Contents:
  • Overview of vaccine effects and study designs
  • Immunology and early phase trials
  • Binomial and stochastic transmission models
  • R[o] and deterministic models
  • Evaluating protective effects of vaccination
  • Models of action and time-varying VE[s]
  • Further evaluation of protective effects
  • Vaccine effects on post-infection outcomes
  • Household-based studies
  • Analysis of households in communities
  • Analysis of independent households
  • Assessing indirect, total, and overall effects
  • Randomization and baseline transmission
  • Surrogates of protection.